Supplements
Evidence-based supplement profiles with gene interactions, mechanisms of action, safety information, and graded research references.
supplement
5-HTP
5-HTP is a supplement referenced across 1 gene profile in the Science of Vitality database.
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AK-7
AK-7 is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Alpha-GPC
Alpha-GPC is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Alpha-Ketoglutarate (AKG)
Alpha-Ketoglutarate (AKG) is a supplement referenced across 2 gene profiles in the Science of Vit...
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Alpha-Lipoic Acid
Alpha-lipoic acid (ALA) is a naturally occurring dithiol compound synthesized in mitochondria tha...
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Ambroxol
Ambroxol is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Anthocyanins
Anthocyanins is a supplement referenced across 1 gene profile in the Science of Vitality database.
View profile arrow_forwardantioxidants and redox support
Antioxidants
Antioxidant nutrients and supplements encompass a broad class of compounds that directly neutrali...
View profile arrow_forwardnatural polyphenols and botanicals
Apigenin
Apigenin is a naturally occurring flavone found abundantly in chamomile, parsley, and celery that...
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Arginine
Arginine is a semi-essential amino acid that plays a critical role in nitric oxide synthesis, pro...
View profile arrow_forwardcarotenoid antioxidants
Astaxanthin
Astaxanthin is a keto-carotenoid produced predominantly as the (3S,3S) stereoisomer by the microa...
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Astragalus Extract
Astragalus Extract is a supplement referenced across 1 gene profile in the Science of Vitality da...
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B-Complex Vitamins
B-Complex Vitamins is a supplement referenced across 3 gene profiles in the Science of Vitality d...
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Bacopa monnieri
Bacopa monnieri is a supplement referenced across 1 gene profile in the Science of Vitality datab...
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Beetroot (Nitrates)
Beetroot (Nitrates) is a supplement referenced across 1 gene profile in the Science of Vitality d...
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Berberine
Berberine is an isoquinoline alkaloid found in goldenseal, barberry, and Oregon grape root that a...
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Bergamot
Bergamot is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Betaine / TMG (trimethylglycine)
Betaine / TMG (trimethylglycine) is a supplement referenced across 2 gene profiles in the Science...
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Biotin
Biotin is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Boron
Boron is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Boswellia Serrata
Boswellia Serrata is a supplement referenced across 4 gene profiles in the Science of Vitality da...
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Bovine Colostrum
Bovine Colostrum is a supplement referenced across 1 gene profile in the Science of Vitality data...
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Butterbur
Butterbur is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Calcium
Calcium is a supplement referenced across 4 gene profiles in the Science of Vitality database.
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Celastrol
Celastrol is a supplement referenced across 3 gene profiles in the Science of Vitality database.
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Centella asiatica (Gotu Kola)
Centella asiatica (Gotu Kola) is a supplement referenced across 1 gene profile in the Science of...
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Choline
Choline is a supplement referenced across 3 gene profiles in the Science of Vitality database.
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Chromium
Chromium is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Cinnamon
Cinnamon is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Cocoa Flavanols
Cocoa Flavanols is a supplement referenced across 1 gene profile in the Science of Vitality datab...
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Collagen Peptides
Collagen Peptides is a supplement referenced across 1 gene profile in the Science of Vitality dat...
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Copper
Copper is a supplement referenced across 3 gene profiles in the Science of Vitality database.
View profile arrow_forwardamino acids and derivatives
Creatine
Creatine is a naturally occurring nitrogenous organic acid that serves as a rapidly mobilizable r...
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Curcumin
Curcumin is a polyphenolic compound from turmeric with potent anti-inflammatory, antioxidant, and...
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Cyanidin
Cyanidin is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Cycloastragenol (TA-65)
Cycloastragenol (TA-65) is a supplement referenced across 1 gene profile in the Science of Vitali...
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Electrolytes
Electrolytes is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Epigallocatechin gallate (EGCG)
Epigallocatechin gallate (EGCG) is the primary bioactive catechin in green tea and one of the mos...
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Exogenous Ketones (BHB salts/esters)
Exogenous Ketones (BHB salts/esters) is a supplement referenced across 1 gene profile in the Scie...
View profile arrow_forwardmacronutrients and prebiotics
Fiber
Dietary fiber comprises a diverse group of non-digestible carbohydrates and lignins that are intr...
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Fisetin
Fisetin (3,3,4,5,7-pentahydroxyflavone) is a naturally occurring flavonoid found in strawberries,...
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Fucoidan
Fucoidan is a supplement referenced across 1 gene profile in the Science of Vitality database.
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GABA
GABA is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Garlic
Garlic (Allium sativum) is an organosulfur-rich botanical supplement whose primary bioactive comp...
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General Micronutrients
General Micronutrients is a supplement referenced across 2 gene profiles in the Science of Vitali...
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Genistein
Genistein is a supplement referenced across 4 gene profiles in the Science of Vitality database.
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Geranylgeranylacetone
Geranylgeranylacetone is a supplement referenced across 1 gene profile in the Science of Vitality...
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Ginger
Ginger is a supplement referenced across 3 gene profiles in the Science of Vitality database.
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Ginkgo biloba
Ginkgo biloba is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Ginsenoside Mc1
Ginsenoside Mc1 is a supplement referenced across 1 gene profile in the Science of Vitality datab...
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Glucosylceramide Synthase Inhibitors
Glucosylceramide Synthase Inhibitors is a supplement referenced across 1 gene profile in the Scie...
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Glutamine
Glutamine is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Glutathione
Glutathione is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Goldenseal (Avoid)
Goldenseal (Avoid) is a supplement referenced across 1 gene profile in the Science of Vitality da...
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Grape Seed Extract (Procyanidin C1)
Grape Seed Extract (Procyanidin C1) is a supplement referenced across 1 gene profile in the Scien...
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Gynostemma (Jiaogulan)
Gynostemma (Jiaogulan) is a supplement referenced across 1 gene profile in the Science of Vitalit...
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High-Fiber / SCFAs
High-Fiber / SCFAs is a supplement referenced across 1 gene profile in the Science of Vitality da...
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Idebenone
Idebenone is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Indole-3-Carbinol (I3C)
Indole-3-Carbinol (I3C) is a supplement referenced across 2 gene profiles in the Science of Vital...
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Iodine
Iodine is a supplement referenced across 4 gene profiles in the Science of Vitality database.
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IP-6 (Phytic Acid)
IP-6 (Phytic Acid) is a supplement referenced across 1 gene profile in the Science of Vitality da...
View profile arrow_forwardessential minerals
Iron
Iron is an essential trace mineral required for the synthesis of hemoglobin and myoglobin, making...
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Isoflavones (Soy)
Isoflavones (Soy) is a supplement referenced across 1 gene profile in the Science of Vitality dat...
View profile arrow_forwardmitochondrial support
L-Carnitine
L-carnitine is a conditionally essential trimethylamine amino acid derivative biosynthesized from...
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L-Citrulline
L-Citrulline is a supplement referenced across 1 gene profile in the Science of Vitality database.
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L-methylfolate (5-MTHF)
L-methylfolate (5-MTHF) is a supplement referenced across 1 gene profile in the Science of Vitali...
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L-Tyrosine
L-Tyrosine is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Lactoferrin
Lactoferrin is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Lactotripeptides
Lactotripeptides is a supplement referenced across 1 gene profile in the Science of Vitality data...
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Leucine
Leucine is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Lithium
Lithium is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Luteolin
Luteolin is a supplement referenced across 1 gene profile in the Science of Vitality database.
View profile arrow_forwardessential minerals
Magnesium
Magnesium is the fourth most abundant mineral in the human body and a required cofactor for more...
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Manganese
Manganese is a supplement referenced across 1 gene profile in the Science of Vitality database.
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MCT Oil
MCT Oil is a supplement referenced across 1 gene profile in the Science of Vitality database.
View profile arrow_forwardcircadian and sleep support
Melatonin
Melatonin is a tryptophan-derived indoleamine hormone synthesized primarily by the pineal gland i...
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Methylene Blue
Methylene Blue is a supplement referenced across 2 gene profiles in the Science of Vitality datab...
View profile arrow_forwardbotanicals and adaptogens
Milk Thistle (Silybum marianum)
Milk thistle is an herbal supplement derived from the Silybum marianum plant, recognized primaril...
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Mucuna pruriens
Mucuna pruriens is a supplement referenced across 1 gene profile in the Science of Vitality datab...
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Multivitamins
Multivitamins is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Myo-Inositol
Myo-Inositol is a supplement referenced across 4 gene profiles in the Science of Vitality database.
View profile arrow_forwardantioxidants and redox support
NAC (N-Acetylcysteine)
N-acetylcysteine (NAC) is a cysteine derivative and FDA-approved mucolytic and acetaminophen anti...
View profile arrow_forwardnad and mitochondrial support
NAD+ Precursors (NMN/NR)
NAD+ precursors, principally nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), ar...
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Nattokinase
Nattokinase is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Niacin (Vitamin B3)
Niacin (Vitamin B3), specifically in its nicotinic acid form, is a water-soluble B-vitamin and po...
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Nicotinamide (NAM)
Nicotinamide (NAM) is a supplement referenced across 1 gene profile in the Science of Vitality da...
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NMN
NMN is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Nobiletin
Nobiletin is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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NR (Nicotinamide Riboside)
Nicotinamide Riboside (NR) is a vitamin B3 analog and the most bioavailable oral precursor to NAD...
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Nucleoside Precursors
Nucleoside Precursors is a supplement referenced across 1 gene profile in the Science of Vitality...
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Omega-3 Fatty Acids
Omega-3 fatty acids, principally EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) from...
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Pantethine
Pantethine is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Phosphatidylcholine
Phosphatidylcholine is a supplement referenced across 1 gene profile in the Science of Vitality d...
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Piperlongumine
Piperlongumine is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Potassium
Potassium is a supplement referenced across 3 gene profiles in the Science of Vitality database.
View profile arrow_forwardmitochondrial support
PQQ (Pyrroloquinoline Quinone)
Pyrroloquinoline quinone (PQQ) is a redox-active quinone cofactor first identified in bacterial s...
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Probiotics
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health b...
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Pycnogenol
Pycnogenol is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Quercetin
Quercetin is a ubiquitous dietary flavonol found in onions, apples, berries, and capers that has...
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Red Yeast Rice
Red Yeast Rice is a supplement referenced across 2 gene profiles in the Science of Vitality datab...
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Resistant Starch
Resistant Starch is a supplement referenced across 1 gene profile in the Science of Vitality data...
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Resveratrol
Resveratrol is a stilbene polyphenol found in grape skins, red wine, and Japanese knotweed that h...
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Rhein
Rhein is a supplement referenced across 1 gene profile in the Science of Vitality database.
View profile arrow_forwardessential vitamins
Riboflavin (Vitamin B2)
Riboflavin is a water-soluble B vitamin that serves as the essential core for the flavin adenine...
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SAMe (S-Adenosylmethionine)
S-adenosylmethionine (SAMe) is the universal methyl donor in human biochemistry, synthesized endo...
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Selenium
Selenium is an essential trace mineral that serves as the mandatory structural component of selen...
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Short-Chain Fatty Acids (Butyrate)
Short-Chain Fatty Acids (Butyrate) is a supplement referenced across 1 gene profile in the Scienc...
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Silica
Silica is a supplement referenced across 1 gene profile in the Science of Vitality database.
View profile arrow_forwardlongevity and autophagy
Spermidine
Spermidine is a naturally occurring polyamine found in all living cells that has emerged as one o...
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St. John's Wort
St. John's Wort (Hypericum perforatum) is an herbal supplement traditionally used for mild depres...
View profile arrow_forwardphytonutrients and plant extracts
Sulforaphane
Sulforaphane is an isothiocyanate produced when glucoraphanin in cruciferous vegetables, particul...
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Thymidine
Thymidine is a nucleoside used in rescue therapy for mitochondrial DNA depletion syndromes, parti...
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Trehalose
Trehalose is a naturally occurring non-reducing disaccharide that functions as a chemical chapero...
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TUDCA
TUDCA is a supplement referenced across 1 gene profile in the Science of Vitality database.
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Ubiquinol/CoQ10 (Coenzyme Q10)
Coenzyme Q10 (CoQ10, ubiquinone) is a fat-soluble quinone synthesized endogenously in virtually a...
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Urolithin A
Urolithin A is a supplement referenced across 3 gene profiles in the Science of Vitality database.
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Vitamin A (Retinol)
Vitamin A (Retinol) is a supplement referenced across 1 gene profile in the Science of Vitality d...
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Vitamin B12 / Folate
Vitamin B12 (cobalamin) and folate (vitamin B9) are water-soluble vitamins that serve as essentia...
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Vitamin B6 (P5P)
Vitamin B6 (P5P) is a supplement referenced across 2 gene profiles in the Science of Vitality dat...
View profile arrow_forwardvitamins and essential nutrients
Vitamin C
Vitamin C (ascorbic acid) is an essential water-soluble vitamin that functions as a potent antiox...
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Vitamin D3
Vitamin D3 (cholecalciferol) is a fat-soluble secosteroid hormone precursor synthesized in skin u...
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Vitamin E
Vitamin E is a collective term for eight naturally occurring fat-soluble compounds (four tocopher...
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Vitamin K
Vitamin K is a supplement referenced across 2 gene profiles in the Science of Vitality database.
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Whey Protein
Whey Protein is a supplement referenced across 1 gene profile in the Science of Vitality database.
View profile arrow_forwardessential minerals
Zinc
Zinc is an essential trace mineral required for the catalytic activity of over 300 enzymes and th...
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