Biological Pathways & Mechanisms

Understand the biological mechanisms that connect your genes to your health outcomes.

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About This Hub

Pathways are the connective middle layer where genes, molecules, and physiology meet. Each pathway section maps mechanisms to their upstream genes and downstream health effects.

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Metabolic

Glucose, lipids, mitochondria, one-carbon metabolism

endocrinology

Hormonal

HPA axis, thyroid, insulin/IGF, circadian

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Immune & Inflammatory

Innate/adaptive immunity, oxidative stress, gut-immune axis

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Cellular

Cell signaling, apoptosis, autophagy, DNA repair

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Aging & Longevity

Hallmarks of aging, senescence, telomeres, epigenetic clocks

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Neurotransmitters

Dopamine, serotonin, GABA/glutamate